New COVID-19 treatment option for non-hospitalised highest risk children and young people

Earlier this week, a new COVID-19 treatment became available across the UK for non-hospitalised children and young people aged 12 and over at the highest risk of severe COVID-19.

The UK-wide policy details those patients who are at the highest risk of severe disease and could be considered for treatment with Sotrovimab, a neutralising monoclonal antibody treatment. 

The College’s advice on clinical management of children and young people with COVID-19 has been updated to reflect these developments. Table 2 in the Treatment criteria for COVID-19 specific therapy section outlines additional considerations the clinical risk factors that should be considered when recommending treatment to non-hospitalised symptomatic, SARS-CoV-2 PCR positive children and young people. 

Integrated Care Systems, Health Boards and Trusts across the UK are establishing referral pathways and services - COVID Medicines Delivery Units (CMDU) – to provide timely assessment and access to treatment for those patients who can benefit (see below for further signposts by  nation).

For children and young people, this rapid assessment should be undertaken by a paediatric multi-disciplinary team (MDT). Paediatricians may be approached by parents and families concerned about whether a child or young person is eligible for treatment should they test positive for SARS-CoV-2. Any concerned clinician should refer to their regional MDT for support and advice.

Further information: