BPSU - HIV infection and perinatal HIV exposure

The BPSU facilitates surveillance of paediatric HIV infection and perinatal HIV exposure in the UK and Ireland. Surveillance began in 1986 and is carried out by the National Study of HIV in Pregnancy & Childhood (NSHPC) who collect case notifications and data through a combination of active paediatric and obstetric reporting schemes.

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NSHPC team

Helen Peters, Rebecca Sconza, Anna Horn, Kate Francis (pictured left to right)

NSHPC principal investigator

Dr Claire Thorne

NSHPC contact details

Population, Policy and Practice Programme
UCL Great Ormond Street Institute of Child Health
30 Guilford Street
London, WC1N 1EH

Tel: 0207 905 2815
Email: nshpc@ucl.ac.uk
Web: www.ucl.ac.uk/nshpc

Overview

The BPSU reporting system is a key part of paediatric reporting of HIV in the UK and Ireland. All children presenting with HIV infection, regardless of place of birth or mode of acquisition of infection, should be reported, as well as all infants born to HIV positive women in the UK and Ireland, regardless of infection status. The BPSU provides case  notifications to the National Study of HIV in Pregnancy & Childhood (NSHPC), thereby facilitating data collection for national HIV paediatric surveillance. Such data contributes to a wide range of epidemiological and clinical analyses and publications, including assessments of the impact of antenatal screening and the uptake of interventions in pregnancy and the monitoring of developments in the management of infected and exposed children.

Case definition: 

1) Any child under 16 years of age who has HIV infection (regardless of country of birth)

OR

2) Any child born to a woman known to have been diagnosed with HIV by the time of that child's birth (regardless of the child's infection status).

Reporting instructions: Please report children seen in the last month (or that you have not previously reported to the BPSU) who meet the case definition.

Duration: Surveillance began in June 1986 and is ongoing. 

Funding: Funding is provided by Public Health England and the Infectious Diseases Screening Programme (www.gov.uk/guidance/infectious-diseases-in-pregnancy-screening-programme-overview).

Ethical approval: The London Multicentre Research Ethics Committee approved the NSHPC and the associated CHIPS study (London MREC/04/2/009; MREC/04/2/010); annual reports are submitted. Data can be provided to the NSHPC by PCTs and NHS Trusts under the exemption specified in the STD Regulations 2000; NIGB (Ref: PIAG/BPSU 2-10(a)/2005) has approved data collection from sources other than PCTs and NHS Trusts. For further details see http://www.ucl.ac.uk/nshpc/ethics

Current results

NSHPC data is presented widely at national and international conferences.

Support group

Further information