Research

JDRF – Clinical Trials to Advance Therapies for Nephropathy and Cardiovascular Disease in Type 1 Diabetes

Despite advanced technologies to maintain glucose control, long-term complications such as diabetic nephropathy (DN) and cardiovascular disease (CVD) are still the primary cause of morbidity and mortality in people with T1D. There is currently a lack of targeted therapies for DN or CVD approved for use by people with T1D, in part because people with T1D are seldom included in drug trials for these diabetic complications. To fill this gap, JDRF invites applications for clinical trials to advance ...
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Over £500,000
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JDRF - Novel Approaches to Address Disordered Eating and Eating Disorders in Type 1 Diabetes

People with T1D have a 2-3 fold higher risk of developing eating disorders than their peers without diabetes, and a significant number of people with T1D have disordered eating behaviors but do not meet full diagnostic criteria for ED. Early detection and targeted prevention strategies could reduce the likelihood of development of a clinical ED. To develop effective approaches to prevention and early intervention models, increased knowledge of the etiology of DEB and ED is needed.
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Over £500,000
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JDRF - Novel Immune Strategies to Enhance Beta Cell Replacement Therapies for T1D

Despite significant progress in the development of alternative renewable sources of insulin producing cells to overcome the shortage of donor tissue, major scientific and technical challenges in overcoming recurring autoimmunity and allogeneic immune rejection remain which must be addressed before beta cell replacement can be widely implemented as a cure for established T1D. The reliance on systemic administration of immunosuppressive drugs to protect the cell graft from the recipient’s immune r...
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£250,001 to £500,000
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Basic page

Neonatal stroke presenting/diagnosed in the first 90 days of life

Surveillance of neonatal stroke is to commence in autumn of 2021. The study is led by Tizard bursary winner Dr T’ng Kwok and will provide a current description of neonatal stroke including the associated factors, management and outcomes. By exploring how babies with neonatal stroke present and are c...
Event

SPS St Andrew's Day Paediatric Symposium

12 November 2021
The Scottish Paediatric Society Annual General Meeting and the St Andrew’s Day Paediatric Symposium will be held online. It will have four clinical case and four QI/Audit/Research presentations, poster presentations and two guest speakers, including Dr Camilla Kingdon, RCPCH President. Abstract s...